Ruilin Tian

Ruilin Tian, Kampmann lab, UCSF

[email protected]

Graduate Student, Biophysics

Education:

  • PhD candidate in the Biophysics program, University of California, San Francisco
  • B.S. in Biological Science, Peking University

Research Experience:

  • Ou laboratory, School of Life Sciences, Tsinghua University Nov. 2014 – Jul. 2015
    • Investigated genes involved in cilliogenesis in C.elegans sensory neurons
  • Kennedy laboratory, Buck Institute for Research on Aging Sept. 2014 –Nov. 2014
    • Investigated the effect of tryptophan uptake on aging in C. elegans and mammalian cells
  • Derry laboratory, Department of Molecular Genetics, University of Toronto Jul. 2014 – Sept. 2014
    • Investigated the role of CCM-3 in C. elegans germline development
  • Ouyang laboratory, Center for Quantitative Biology, Peking University Sept. 2013 – Jul. 2014
    • Genome-wide study of intracellular NADPH level regulation and its impact on aging
    • Investigated key transcription factors in replicative life span regulation in S. cerevisiae
    • Investigated the mechanism of accelerated aging in budding yeast induced by telomerase inactivation

Honors and Awards:

  • Tau Consortium Fellowship, 2016
  • National Scholarship, Oct. 2014
  • May Fourth Scholarship, Oct. 2013
  • Third prize in the 3rd Summer Social Practice, Sept. 2012
  • First prize in Biology Field Practice, Jul. 2012

Publications:

  1. Xie, Z., Jay, K.A., Smith, D.L., Zhang, Y., Liu, Z., Zheng, J., Tian, R., Li, H. and Blackburn, E.H., 2015. Early telomerase inactivation accelerates aging independently of telomere length. Cell, 160(5), pp.928-939.
  2. He, C., Tsuchiyama, S.K., Nguyen, Q.T., Plyusnina, E.N., Terrill, S.R., Sahibzada, S., Patel, B., Faulkner, A.R., Shaposhnikov, M.V ., Tian, R. and Tsuchiya, M., 2014. Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import. PLoS Genet, 10(12), p.e1004860.
  3. Mavor, D., Barlow, K., Asarnow, ...Tian, R., …, & Nelson, C. A. ,2017. Extending Chemical Perturbations Of The Ubiquitin Fitness Landscape In A Classroom Setting. bioRxiv, p.139352.
  4. Pal, S., Lant, B., Yu, B., Tian, R., Tong, J., Krieger, J.R., Moran, M.F., Gingras, A.C. and Derry, W.B., 2017. CCM-3 promotes C. elegans germline development by regulating vesicle trafficking cytokinesis and polarity. Current Biology, 27(6), pp.868-876.
  5. Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nat Biotechnol. 2018 Jan 15. doi: 10.1038/nbt.4062. [Epub ahead of print] PubMed PMID: 29334369.

Teaching Experience:

  • Teaching Assistant Biophysics 205A: Physical Underpinnings of Biological Systems, 2016

Other interests:

Playing basketball, windsurfing, watching movies and traveling.