[email protected]
She/her/hers
Graduate Student, Chemistry and Chemical Biology Program
Joint with Gestwicki lab
Education:
B.Sc. in Biochemistry, Heidelberg University, Germany (2024)
Previous Research Experience:
- Sunbul Group, Heidelberg University (2023-2024)
- Developed methods for simultaneous high-resolution imaging of RNA, DNA, and proteins using fluorescent microscopy. Worked on optimizing a photocatalytic proximity labeling procedure to determine the proteins interacting with specific RNA.
- Computational Carbon Chemistry Group, Heidelberg Institute for Theoretical Studies (2023)
- Created a machine learning model to predict partial atomic charges of N -heteropolycyclic compounds
- Enamine Ltd. (2020-2021)
- Developed new organic chemistry reaction protocols
Publications:
- Chalyk, B., Grynyova, A., Filimonova, K., Rudenko, T. V., Dibchak, D., & Mykhailiuk, P. K. (2022). Unexpected isomerization of oxetane-carboxylic acids. Organic Letters, 24(26), 4722–4728.
- Chalyk, B. A., Khutorianskyi, A. V., Vashchenko, B. V., Danyleiko, K., Grynyova, A., Osipova, A. O., Kozytskiy, A., Syniuchenko, D., Tsymbaliuk, A., Gavrilenko, K. S., Biitseva, A. V., Volochnyuk, D. M., Komarov, I. V., & Grygorenko, O. O. (2021). Reductive recyclization of SP3-enriched functionalized isoxazolines into α-hydroxy lactams. The Journal of Organic Chemistry, 87(2), 1001–1018.
Research interests:
Coming from a chemistry background, I like to think about biological systems at the molecular level. One of the most mysterious molecules in biology is the tau protein, whose aggregation leads to several neurodegenerative diseases. I am interested in exploring which factors lead to its aggregation, why it occurs differently across distinct brain cell types, and whether we can reverse neurodegeneration through pharmacological intervention.
Interests:
Figure skating, yoga, hiking, baking, learning languages