Gary Dixon, PhD

Gary Dixon, Kampmann lab

[email protected]
he/him/his
Postdoctoral Fellow
A.P. Giannini Postdoctoral Fellow

Education

  • PhD, Cell and Developmental Biology – Weill Cornell Medicine, 2021
  • MRes, Systems and Synthetic Biology – Imperial College London, 2012
  • BA, Molecular and Cell Biology – University of California Berkeley, 2011

Publications

  • Yang D., Cho H., Tayyebi Z., Shukla A., Luo R., Dixon G., Ursu V., Stransky S., Tremmel D.M., Sackett S.D., Koche R., Kaplan S.J., Li Q.V., Park J., Zhu Z., Rosen B.P., Pulecio J., Shi Z.D., Bram Y., Schwartz R.E., Odorico J.S., Sidoli S., Wright C.V., Leslie C.S., Huangfu D. CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nat Cell Biol 2022, 24(7):1064-1076. https://doi.org/10.1038/s41556-022-00946-4.
  • Dixon, G.; Pan, H.; Yang, D.; Rosen, B. P.; Jashari, T.; Verma, N.; Pulecio, J.; Caspi, I.; Lee, K.; Stransky, S.; Glezer, A.; Liu, C.; Rivas, M.; Kumar, R.; Lan, Y.; Torregroza, I.; He, C.; Sidoli, S.; Evans, T.; Elemento, O.; Huangfu, D. QSER1 Protects DNA Methylation Valleys from de Novo Methylation. Science 2021, 372 (6538). https://doi.org/10.1126/science.abd0875.
  • Lan Y., Banks K.M., Pan H., Verma N., Dixon G.R., Zhou T., Ding B., Elemento O., Chen S., Huangfu D., Evans T. Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation. Cell Rep 2021, 37 (10):110095. https://doi.org/10.1016/j.celrep.2021.110095.
  • Li, Q. V.; Dixon, G.; Verma, N.; Rosen, B. P.; Gordillo, M.; Luo, R.; Xu, C.; Wang, Q.; Soh, C.-L.; Yang, D.; Crespo, M.; Shukla, A.; Xiang, Q.; Dündar, F.; Zumbo, P.; Witkin, M.; Koche, R.; Betel, D.; Chen, S.; Massagué, J.; Garippa, R.; Evans, T.; Beer, M. A.; Huangfu, D. Genome-Scale Screens Identify JNK-JUN Signaling as a Barrier for Pluripotency Exit and Endoderm Differentiation. Nat Genet 2019, 51 (6), 999–1010. https://doi.org/10.1038/s41588-019-0408-9.
  • Song, R.; Walentek, P.; Sponer, N.; Klimke, A.; Lee, J. S.; Dixon, G.; Harland, R.; Wan, Y.; Lishko, P.; Lize, M.; Kessel, M.; He, L. MiR-34/449 MiRNAs Are Required for Motile Ciliogenesis by Repressing Cp110. Nature 2014, 510 (7503), 115–120. https://doi.org/10.1038/nature13413.

Honors and Awards

  • A.P. Giannini Postdoctoral Fellowship, 2022
  • Julian R. Rachele Prize, Weill Cornell Medicine, 2021
  • Frank Lappin Horsfall Jr. Fellowship, Weill Cornell Medicine, 2018

Research Interests

In Alzheimer’s disease and related dementias, cells in the brain can acquire abnormal epigenetic states. We are just beginning to understand the origin and consequences of those molecular changes. Therefore, huge potential exists for discovery and characterization of disease-relevant epigenetic mechanisms. Using stem cell models and CRISPR screening, I intend to uncover the drivers of these mechanisms, ultimately leading to expansion of therapeutic targets.

Other Interests

My favorite thing is spending time with family and friends, eating, playing games, and generally enjoying the company of the best people in the world (sorry everyone else). I am a lover of nature, Ultimate Frisbee, playing music, and chess!