Medical student at Heidelberg University, Germany
Tauopathies, including Alzheimer’s disease are a broad set of diseases characterized by the deposition of aggregated tau protein and progressive neurodegeneration. Despite the discovery of neurofibrillary tangles composed of tau in patients with dementia as early as 1906, the cause of these pathological assemblies is not well understood. The goal of my internship is to help unravel this puzzle using genome-wide CRISPR screens to identify genes that modify tau aggregation in human stem cell-derived neurons.
Gym workouts, soccer, cooking, and reading.