Mor Alkaslasi

Mor Alkaslasi, Kampmann lab

[email protected]
Postdoctoral fellow
 

Education

  • PhD in Neuroscience from Brown University-NIH GPP (2024)

  • BS in Neurobiology, Physiology, and Behavior from UC Davis (2016)

 

Selected Publications

Full list of publications​

  • Alkaslasi, MR, Lloyd, E, Gable, AS, Silberberg, H, Yarur, H, Tsai, V, Tejeda, H, Le Pichon, CE. The transcriptional response of cortical neurons to concussion reveals divergent fates after injury. (2024) Preprint, DOI: 10.1101/2024.02.26.581939.

  • Yadav, A, Matson, KJE, Li, L, Hua, I, Petrescu, J, Kang, K, Alkaslasi, MR, Lee, DI, Hasan, S, Galuta, A, Dedek, A, Ameri, S, Parnell, J, Alshardan, MM, Ququmji, FA, Alhamad, SM, Wang, AP, Poulen, G, Lonjon, N, Vachiery-Lahaye, F, Gaur, P, Nalls, MA, Ward, ME,  Hildebrand, ME, Mery, PF, Bourinet, E, Bauchet, L, Tsai, EC, Phatnani, H, Le Pichon, CE, Menon, V, Levine, AJ. (2023). A Cellular Taxonomy of the Adult Human Spinal Cord. Neuron. Feb 1;111(3).

  • Alkaslasi, MR*, Piccus, ZE*, Hareendran, S, Silberberg, H, Chen, L, Zhang, Y, Petros, TJ, Le Pichon, CE. (2021). Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord. Nature Communications. Apr 30; 12(2471).*, Piccus, ZE*, Hareendran, S, Silberberg, H, Chen, L, Zhang, Y, Petros, TJ, Le Pichon, CE. (2021). Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord. Nature Communications. Apr 30; 12(2471).

  • Alkaslasi, MR, Cho, NE, Dhillon, NK, Shelest, O, Haro-Lopez, P, Linaval, NT, Ghoulian, J, Yang, AR, Vit, JP, Avalos, P, Ley, E, Thomsen, GM. (2021). Poor corticospinal motor neuron health is associated with increased symptom severity in the acute phase following repetitive mild TBI and predicts early ALS onset in genetically predisposed rodents. Brain Sciences. Jan 26; 11(2), 160.

  • Thomsen, GM, Gowing, G, Latter, J, Chen, M, Vit, JP, Staggenborg, K, Avalos, P, Alkaslasi, M, Ferraiuolo, L, Likhite, S, Kaspar, B, Svendsen, C. (2014). Delayed disease onset and extended survival in the SOD1G93A rat model of ALS following suppression of mutant SOD1 in the motor cortex. Journal of Neuroscience. Nov 19;34(47):15587-600.

 

Research Interests

A key feature of multiple neurodegenerative conditions is the selective vulnerability of specific types of neurons to pathology and death. In ALS, motor neurons in the cortex and spinal cord degenerate while, in Alzheimer’s disease, it's neurons in the cortex and hippocampus. I am interested in uncovering the biological mechanisms underlying the vulnerability of neurons in tauopathies.

 

Other interests

I enjoy martial arts, tennis, reading, and hiking with my dog.